Soma pills for treating muscle pain

How to avoid soma side effects?

This drug should be ingested in the exact manner as recommended by the qualified medical practitioner. To prevent the symptoms of serious side effects from showing up, do not take it in higher amounts than prescribed or for a longer time period and in deceased time intervals. Soma pills are very effective in treating muscle injury and spasms.

Some severe side effects of this medication include fever, burning sensation in the eyes, problem in breathing and weakness. If any these symptoms surface, do not waste time and get in touch with the medical practitioner immediately. If ingested in very big amounts, this medication may cause an overdose of meprobamate that can lead to coma.

If you ingest it for a long period of time, it is possible that you might develop tolerance to this medication. Hence, you may experience moderate withdrawal reactions that can continue for two to four days post ingestion of the last dose.

Soma stays in your system for how long:

On sudden discontinuation of this medication after taking it for a considerably long duration,   it is possible for you to experience moderate withdrawal reactions 12 to 48 hours post taking the last soma dosage. These symptoms can be visible for next 12 to 48 hours. Meprobamate as well as carisoprodol is detectable either on a screen for prescription or over-the-counter medications in urine and blood. This may also be done in incidents of suspected overdose. In case you are ingesting a combination drug that also contains codeine, it will be detected.

Clinical pharmacology of Soma

It has been seen in the clinical trials that the relaxation in muscles brought about by carisoprodol, a centrally acting muscle relaxant, is linked with changes in the interneuronal activity in the spinal cord and also in the falling reticular formation of the brain. Carisoprodol does not directly relax the skeletal muscles. Its metabolite, meprobamate, comes with sedative and anxiolytic properties. The average time for carisoprodol concentrations to yield maximum therapeutic results is between 1.5 to 2 hours.

This medication may be taken either with food or without food as co-administration of a meal with soma 350 mg pill had absolutely no effect on the carisoprodol pharmacokinetics.

The main pathway of carisoprodol metabolism is through the liver by CYP2C19, the cytochrome enzyme, to form meprobamate. This enzyme shows genetic polymorphism. The half-life of this carisoprodol metabolite is around ten hours.

Skeletal Muscle Pain

Order soma to treat skeletal muscle pain

Soma is a prescription medication that is taken for relaxing muscles, thereby relieving pain from the muscle spasms.  It is taken as short-term treatment for a time period extending up to three weeks. To effectively treat acute muscle pain and associated discomfort, order soma online.

Interaction of soma with other Drugs

The sedative effects of this medication along with other CNS depressants such as benzodiazepines, tricyclic antidepressants, alcohol and opioids can be additive. Thus, care should be taken in patients who simultaneously ingest more than one CNS depressant.  Simultaneous use of meprobamate, a metabolite of soma and the soma drug must be strictly avoided.

Carisoprodol, the primary ingredient in soma, gets metabolized by CYP2C19 in the liver to form meprobamate. Co-administration of CYP2C19 inhibitors, for example, fluvoxamine or omeprazole with soma may cause reduced exposure of meprobamate and greater exposure of carisoprodol.  On the other hand, co-administration of CYP2C19 inducers, for example, St. John’s wort or rifampin with this medication may lead to greater exposure of meprobamate and reduced exposure of carisoprodol. Low dose of aspirin is also a CYP2C19 inducer.

Drug Abuse

Carisoprodol, marketed under the brand name soma, is a schedule four controlled substance.  Abuse of this drug may lead to overdose, ultimately causing death, low blood pressure, central nervous system and respiratory depression, seizures and also other disorders. Individuals who are ingesting soma for a long period of time, those who are taking this drug along with other abused medications or who have a history of drug abuse face a greater risk of soma abuse.

Is Soma Addictive?

Addiction to the drug develops after continual drug abuse, and is characterized by an intense desire to ingest this medication in spite of its detrimental effects, attaching higher priority to drug usage rather than to obligations, greater tolerance for the drug, problem in controlling its usage and at times, physical withdrawal also.

Drug Dependence

When your response to this drug dose and concentration is decreased in the absence of any development in the disease, and then you increase the Soma Dosage to get the same results, you have developed tolerance to the drug. Physical dependence is characterized by withdrawal reactions that surface after the dose has been significantly reduced or the treatment has been suddenly stopped. Incidents of physical dependence and tolerance have been seen with the long-term use of this medication. Withdrawal reactions include abdominal cramps, insomnia, tremors, vomiting, anxiety, headache, ataxia, tremors, hallucinations, muscle twitching, and psychosis.

Order Soma Online

Soma pain medicine to treat musculoskeletal pain

Carisoprodol, a centrally acting muscle relaxant, is a prescription medication marketed since 1959. It is taken for the treatment of painful acute skeletal muscle conditions in combination with physical therapy, rest and other measures. Soma pain medicine is very effective in deal with muscle pain and injuries. It is a schedule IV controlled substance since January 11, 2012.

This drug is available as single-entity pills that contain 250 mg or 350 mg carisoprodol or as combination pills containing 200 mg carisoprodol, 16 mg codeine phosphate, and 325 mg aspirin.

As per IMS health, around 8.5 million carisoprodol products were dispensed in the United States in the year 2013. The standard soma dosage is 250 mg to 350 mg three times a day and before going to bed for adults. It should not be administered to children under the age of sixteen years and to older adults above the age of 65 years.

Pharmacology:

Carisoprodol does not have a direct effect on skeletal muscle in human beings. The skeletal muscle relaxant action of this drug may be linked to its sedative properties. It is a fast-acting medication and its effects last for four to six hours. It is broken down in the liver and eliminated by way of kidneys. Carisoprodol’s major metabolic pathway entails its conversion to meprobamate, a medication with barbiturate-like biological actions.

What are the contraindications associated with soma use?

Soma medication is contraindicated in individuals with a history of intermittent acute porphyria or who are hypersensitive to a carbamate such as meprobamate.

Use of soma in lactating women

Limited data is human beings have shown that this drug passes into the breast milk and can reach concentrations two to four times the maternal plasma concentrations. According to a case report, a breast-fed infant received around four to six percent of the maternal dose per day by way of breast milk but did not experience harmful effects. However, the production of milk was not adequate and the infant was supplemented with formula. This information shows that the use of soma in lactating women may result in reduced infant feeding because of sedation and also decrease in milk production. Extra caution should be taken on administering this medication to lactating mothers.

Use of soma in people with renal impairment

As this drug is eliminated by the kidneys, extra care should be taken in case soma is given to patients with impaired kidney function. Carisoprodol, the primary ingredient in the drug, is dialyzable by peritoneal dialysis hemodialysis.

Use of soma in people with hepatic impairment

This drug is broken down in the liver; hence extra caution should be taken if it is administered to individuals with impaired liver function.

Use of soma in patients with decreased CYP2C19 activity

Individuals with decreased CYP2C19 activity have a greater exposure to carisoprodol. Thus, care should be taking while giving this medication to such patients.

What are the abuse rates of soma and alcohol?

According to an old study between the years 1986 to 1997, 24 deaths were reported from overdose that occurred from the combination of alcohol, soma and sometimes, benzodiazepines. The American Association of Poison Control Centers reported two deaths from exposure to carisoprodol in the year 2012.

As per the report by the National Highway traffic Safety Administration (NHTSA), individuals who ingest this drug, particularly at substantially big or recreational doses, are quite likely to suffer from driving impairment. The effects of the drug on driving are similar to the effects of alcohol. However, soma drugcannot be detected through a breathalyzer test.

Fatal side effects occurring from drug abuse that can be worsened if taken with alcohol include:

1. Facial flushing
2. A head rush as blood pressure drops
3. Tachycardia
4. Respiratory distress

Long-term harm from mixing soma and alcohol:

Combining any medication with alcohol may result in fast damage to the kidneys as well as liver. Alcohol abuse for many years may damage the liver, leading to poor appetite, loss of energy, weight loss, fatigue, belly pain, jaundice, nausea and also difficulty in processing toxins through your body. With the failing liver, the kidneys try to filter out the toxins missed by the liver. Normally, kidneys do not perform this function; hence it can cause damage to the kidneys and even failure. Both these conditions may prove life-threatening.

When you combine alcohol with medications, including soma, the liver needs to process additional chemicals. As a consequence, liver can get damaged which in turn, can also lead to kidney damage. In addition to this, both alcohol and soma, may lead to memory problems, hence loss of memory is quite likely when both the substances are taken for non-medical purposes.

The long-term effects of carisoprodol abuse include the following:

1. Gastrointestinal damage
2. Trouble with speech
3. Cardiovascular damage
4. Transient quadriplegia (spinal damage due to hypertension of the neck)
5. Temporary loss of vision or double vision

Drug abuse and dependence:

Discontinuation of this drug post chronic administration may lead to the occurrence of withdrawal symptoms. Further, there are published reports of carisoprodol dependence in human beings. In vitro studies have shown that this drug exhibits barbiturate-like effects. Soma pills are very effective in providing relief from the discomfort and muscle pain.

Buy Soma Online to Treat Muscle Pain

Soma Online

Soma is taken to get relief from discomfort related with acute painful skeletal muscle conditions. This medication should only be administered for short-term treatment with the time period not exceeding three weeks as its effectiveness in the long-term is yet to be established. Further, these painful skeletal muscle conditions are usually of short duration. Buy soma online if you want to avoid the hassle of going to the drug store.

Dosage forms and strengths

This drug is available in the strength of 250 mg and 350 mg tablets. The 250 mg pills are white, convex and round with SOMA 250 inscribed on it. The 350 mg tablets are also white, round and convex with SOMA 350 inscribed on it.

Dosage and administration

The prescribed dose of soma medication is 250 mg to 350 mg thrice a day and before going to bed. You should not take it for more than three weeks.

What are the warnings and precautions associated with soma use?

Soma pain medicine has sedative properties and may also have a detrimental effect on the physical and mental capabilities needed to undertake potentially dangerous activities such as operating heavy machinery and driving a motor vehicle. Post-marketing incidents of motor vehicle accidents related with the use of this drug have been reported.

There is a possibility of sedative effects of soma drug and other CNS depressants such as benzodiazepines, tricyclic antidepressants, alcohol and opioids being additive, extra care should be taken in patients who ingest more than one of the above mentioned CNS depressants simultaneously.

Incidents of withdrawal, dependence and abuse associated with prolonged usage of this medication have been reported in its post-marketing experience. Majority of cases of withdrawal, dependence and abuse are seen in patients either with a history of addiction or who have taken this drug along with other medications having abuse potential. Further, post-marketing adverse effects linked with soma abuse have also been reported when taken in the absence of other medications with abuse potential. Withdrawal reactions are reported when you suddenly discontinue the use after taking it for a long period of time. 

Dependence may also be caused by soma as well as meprobamate, one of its metabolite.

To decrease the probability of soma withdrawal, dependence or abuse, it should be administered with care in patients prone to addiction and who take other CNS depressants such as alcohol. It should also not be given for a time duration exceeding three weeks to relieve the symptoms of acute painful musculoskeletal discomfort.

Seizures have also been reported in patients who are taking soma medicine. May of such incidents have taken place during multiple drug overdose including illegal drugs, drugs of abuse and alcohol.

What are the side effects associated with soma use?

If you do not ingest this drug in the exact manner as prescribed, it may lead to the occurrence of harmful side effects. These include:

1. Central nervous system: dizziness, ataxia, drowsiness, vertigo, tremors, irritability, agitation, headache, syncope, seizures, depressive reactions and insomnia.
2. Hematologic: pancytopenia, leukopenia
3. Cardiovascular: postural hypotension, tachycardia, facial flushing
4. Gastrointestinal: vomiting, epigastric discomfort

 

Drug interactions with soma:

There is a probability of the sedative effects of this drug as well as other CNS depressants such as benzodiazepines, tricyclic antidepressants, alcohol and opioids being additive. Hence, care should be taken with patients who ingest more than one of these CNS depressants together with soma pills. It is not advisable to take this medication with its metabolite, meprobamate.

Carisoprodol is broken down in the liver to form meprobamate by CYP2C19. 
Simultaneous administration of CYP2C19 inhibitors, for example, fluvoxamine or omeprazole with soma may lead to reduced exposure of meprobamate and greater exposure of carisoprodol. Similarly, simultaneous administration CYP2C19 inducers, for example, St. John’s Wort or rifampin with this drug may lead to greater exposure of meprobamate and lower exposure of carisoprodol. Induction effect on CYP2C19 was also showed by low dose aspirin.

Use of soma in pregnant women

There is no research data on the usage of this medication in human pregnancy. However, animal studies show that carisoprodol, the muscle relaxant, cross the placenta and causes harmful effects on postnatal survival and fetal growth. Meprobamate, the main metabolite of carisoprodol is an approved anxiolytic.
Any consistent linkage between maternal usage of meprobamate and a greater risk for specific congenital malformations has not been seen in retrospective, post-marketing studies. 

Animal studies have not satisfactorily assessed carisoprodol’s teratogenic effects. No increase was seen in the incidence of congenital malformations observed in reproductive studies in rabbits, rats and mice that were treated with meprobamate. Retrospective, post-marketing studies of carisoprodol metabolite, meprobamate, in human pregnancy were evasive for showing a greater risk of congenital malformations in the first three months. The types of malformations were not consistent throughout studies that showed a higher risk.

In animal studies, carisoprodol decreased postnatal weight gain, fetal weights and also postnatal survival at a maternal dosage equal to 1-1.5 times the human dosage. Behavioral changes that continued to adulthood were seen in rats exposed to meprobamate in-utero. It is advisable to take soma drug during pregnancy only it if probable benefit justifies the risk posed to the fetus.

Side Effects of Soma

Buy soma online to treat musculoskeletal condition

Soma is a drug used for the treatment of pain and stiffness n muscles due to sprains, strains or other muscle injuries. It relaxes the muscles in the body and relieves of the discomfort associated with short-term acute painful bone or muscle condition. In order to stay away from the rush of traffic and avoid missing the dose, buy soma online. However, this medication is prescribed in combination with other treatments such as physical therapy, ample rest and exercise depending on your health condition.
Soma is a prescription drug and is available only on the doctor’s prescription. Carisoprodol, the active ingredient in the medication is a skeletal muscle relaxant and relaxes muscles by acting on the central nervous system (CNS).

What are the side effects of soma?

Like most of the medications, this drug also has two kinds of effects, namely desired and undesired effects. In this case, the desired effect is relaxation of the muscles. As a consequence, pain in the affected area is reduced. Since, the action of this medication takes place in the brain, it may cause nervous system side effects. The probable undesired side effects of this medication include:

1. Lightheadedness
2. Clumsiness
3. Extreme drowsiness
4. Accelerated heart rate
5. Upset stomach
6. Rashes on the skin
7. Headache
8. Vomiting
9. Difficulty in breathing
10. Weakness
11. Fever
12. Burning sensation in the eyes

Obviously, all the side effects of soma are not dangerous, but you must get in touch with the qualified medical practitioner if multiple symptoms outlined above the surface at the same time.
In the case of drug abuse, these side effects become more prominent. One of the risks associated with soma drug abuse is being addictive to it.

Soma drug abuse:

Abuse of this medication may be done in the following ways:

1. Ingestion of carisoprodol in higher doses than prescribed
2. Increasing the frequency of taking carisoprodol on your own without doctor’s consent
3. Taking soma drug without the doctor’s prescription
4. Taking soma on the prescription of someone else
5. Ingestion of soma for recreational use
6. Buying more soma tablets than required using soma coupons

Usually, this medication is ingested orally by its abusers. Many a time they take soma together with other medicines to increase the effects of those medications. The drugs that are commonly abused along with soma include: Codeine, heroin, alcohol, diazepam, meprobamate, hydrocodone, and propoxyphene.

What to do in case of emergency or overdose?

In case the patient shows symptoms linked with soma medication such as seizures, difficulty in breathing, has collapsed or cannot be awakened, you should not waste a minute and seek medical help.

Soma Dosage

Soma pills for the treatment of musculoskeletal condition

Carisoprodol, available in the market under the brand name soma, is used for relaxing muscles in your body and relieve you of the discomfort associated by short-term acute painful bone or muscle conditions. Though this drug is prescribed in combination with other treatments – exercise, rest, physical therapy or any other treatment recommended by the qualified medical practitioner. Soma pills are very effective in the treatment of muscle related injuries.
Soma is a prescription drug and should be taken in the exact manner as prescribed by the doctor. Do not make changes in the amount of medicine taken, or in the frequency or for a longer period of time. On taking it for a long duration, you may become habitual to it, leading to physical or psychological dependence. This drug should be ingested in the short-term treatment spanning two to three weeks.

Dosage considerations:

The dose recommended will vary from person to person. You should not make changes in the dosing pattern unless and until the doctor has advised you to do the same. The amount of medicine that is prescribed to you depends on its strength. Further, the amount of your daily dosage of the medicine, the time interval between two subsequent doses and the time duration for which you ingest this medicine depends on the health issue for which you are taking this drug.
The usual dosage of carisoprodol in adults and children above the age of sixteen years is 250 mg to 350 mg per day and before going to bed.
In the case of children and teenagers below the age of sixteen years, the medication should be taken only as recommended by the doctor.

What to do on missing a dose?

In case you forget to take a regular dose of this soma medication, you should take it as soon as you remember. Though you should skip that dose if the time has come to take the next dose. You should not ingest two doses at the same time as it may result on overdose of the drug.

Points to consider before taking soma:

Prior to starting the treatment with soma drug, you should discuss with the doctor and the following points should be taken into consideration:

1. You should inform the doctor if you are allergic to the drug or to any other substances such as dyes, animals, foods or preservatives.
2. Regarding the administration of this drug in children under the age of sixteen years, its safety and effectiveness is yet to be established. Hence, the medication should be taken under the strict supervision of the medical practitioner.
3. Similarly, in the case of elderly population, the medication should be taken when recommended by the doctor and in exact proportions.
4. You should discuss with the doctor at the onset of the treatment with soma pain medicine in case you suffer from other medical health problems that are mentioned below:

• Liver or kidney disease; in this case the effects of the medication may be enhanced due to gradual removal of the drug from your system.
• If you have a history of porphyria, you should not take soma.
• If you experience seizure, then usage of this drug can worsen it.
• You should also be extra careful while taking this drug if you have a history drug dependence or abuse. You may develop dependence on carisoprodol.

 

What precautions you should take?

• It is mandated that the healthcare professional monitors your response to treatment at regular intervals to ensure that this drug is acting properly and also to check for undesired effects.

• In some individuals, the intake of this medication may lead to the occurrence of drowsiness, dizziness or lack of concentration. In such a situation, you should refrain from undertaking any such hazardous activity or task that requires a high level of concentration such as operating heavy machines or driving a motor vehicle.

• The intake of this medication adds to the effects of other CNS depressants such as antihistamines or drugs for clods and allergies, tranquilizers or sleep medicines, hay fever, medicines for seizures or barbiturates, sedatives, prescription pain drugs or narcotics, anesthetics, and also alcohol.

• Hence, doctor’s discretion is advised if you are taking any of the above-mentioned medications.

• You should not abruptly discontinue the treatment with carisoprodol without consulting the doctor as it may lead to the occurrence of withdrawal reactions. It is advisable to gradually decrease the soma dosage before discontinuing it completely.

• You should get in touch with the doctor if your medical condition does not show signs of improvement in two to three weeks.

Storage and disposal:

You should store the medicine in a closed container at ambient room temperature, away from moisture, heat and direct light. It should not be frozen. Keep it in a place where it is beyond the reach of children. Avoid keeping medicine at home or in workplace that is either outdated or not required anymore. You should ask the healthcare professional how to dispose the drug which is no longer in use.

Soma Without Prescription

Why is Soma prescribed?

Carisoprodol, available in the market under the brand name soma, is a muscle relaxant and is taken along with physical therapy and rest for relaxing muscles and relieving pain and associated discomfort. To get fast relief from strains, sprains and other muscle related injuries, buy soma online.

How soma should be taken?

This medication is available as a tablet and can be taken orally. Usually, it is ingest three times a day and before going to bed at night. It can be ingested either with food or without food. You must take this drug in the exact manner as recommended by the qualified medical practitioner and also follow the instructions given on the prescription label. It is not advisable to increase or decrease the soma dosage on your own.

What precautions to be followed before taking soma?

Prior to starting the treatment with this medication, you must inform the doctor if you are allergic to meprobamate (meprospan, neuramate, equanil and miltown), carisoprodol or any other drugs. You must also let the doctor know the nonprescription as well as prescription drugs you are ingesting, particularly drugs for cough and cold, sedatives, allergies, muscle relaxants, tranquilizers, sleeping pills, and vitamins. 

You must inform the doctor if you are suffering or have suffered in the past from some liver or kidney disease. Tell the doctor in case you are pregnant or have plans of starting a family in the near future. In case you get pregnant during the treatment with soma, consult the doctor immediately. The same holds true in case of lactating mothers. 

You must discuss the therapeutic benefits of the soma medication with the doctor along with the risk of side effects that it poses if you are over the age of 65 years. Normally, elderly population should refrain from ingesting this medication as it is not that effective or safe as other drugs that may be employed in treating the same health condition.

Regular ingestion of this drug can lead to drowsiness. Hence, you are advised not to take up activities and tasks that require a high level of mental alertness such as operating machinery or driving a motor vehicle. You must also bear in mind that alcohol consumption while on the treatment with carisoprodol may increase the effect of drowsiness.

What dietary instruction to be followed?

It is advised to take soma pills with either milk or meal as it may upset the stomach.